Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634003 | 1.00 | FOLH1 (0.57) | FOLH1HDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL19741462 | 1.00 | FOLH1 (0.57) | FOLH1HDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL27630947 | 0.97 | — | — | |
| SCHEMBL1402745 | 0.88 | — | — | |
| SCHEMBL27712598 | 0.87 | TSHR (0.47) | FOLH1HDAC3HDAC1HDAC11HDAC2 | |
| SCHEMBL28138992 | 0.87 | TSHR (0.47) | FOLH1HDAC3HDAC1HDAC11HDAC2 | |
| SCHEMBL28065031 | 0.87 | TSHR (0.47) | FOLH1HDAC3HDAC1HDAC11HDAC2 | |
| SCHEMBL27924265 | 0.84 | TSHR (0.44) | FOLH1HDAC3HDAC1HDAC11HDAC2 | |
| SCHEMBL11348207 | 0.84 | LMNA (0.44) | FOLH1HDAC3HDAC1HDAC11HDAC2 | |
| SCHEMBL27924266 | 0.81 | LMNA (0.41) | FOLH1HDAC3HDAC1HDAC11HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110100440-A1 | Optical Rectification Device and Method of Making Same | WILLIAM MARSH RICE UNIVERSITY (US) | 2011-05-05 | — | — | US | disclosed |