Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560636 | 0.93 | NR1I2 (0.38) | NR1I2PDE4APDE4BPDE4C | |
| SCHEMBL16112424 | 0.80 | NR1I2 (0.49) | NR1I2 | |
| SCHEMBL18560690 | 0.80 | MMP13 (0.40) | NR1I2PDE4APDE4BPDE4C | |
| SCHEMBL19955676 | 0.76 | NR1I2 (0.37) | NR1I2 | |
| SCHEMBL19955759 | 0.76 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL18929725 | 0.74 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL19955789 | 0.74 | NR1I2 (0.37) | NR1I2 | |
| SCHEMBL19955514 | 0.74 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL16112574 | 0.73 | NR1I2 (0.49) | NR1I2 | |
| SCHEMBL18560613 | 0.73 | NR1I2 (0.44) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970274-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-03-01 | — | — | EP | disclosed |