Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94914 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16513159 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8354950 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL612165 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2115743 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTTP53ATAD2 | |
| SCHEMBL1866522 | 0.70 | PDE4A (0.49) | ALDH1A1ADORA2AADORA2BADORA3PDE4A | |
| SCHEMBL41788 | 0.70 | PNP (0.50) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL7037918 | 0.69 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL25381 | 0.69 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL30096461 | 0.69 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4493573-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | Rome Therapeutics, Inc. (US) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023178133-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |
| EP-3135487-A1 | MULTILAYER CONTAINER FOR ENHANCED GAS BARRIER PROPERTIES | The Coca-Cola Company (US) | 2017-03-01 | — | — | EP | disclosed |