Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684288 | 0.91 | ALDH1A1 (0.50) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11270394 | 0.88 | ADORA2B (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL26248657 | 0.87 | ALDH1A1 (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL2115743 | 0.78 | ALDH1A1 (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1866524 | 0.77 | ADORA2A (0.50) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL5616439 | 0.76 | ADORA2B (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7684917 | 0.75 | ALDH1A1 (0.42) | ADORA2BADORA3ALDH1A1TRPA1 | |
| SCHEMBL6676183 | 0.74 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3306010 | 0.74 | ACP1 (0.55) | PDE4APDE4BPDE4CPDE4DADORA2B | |
| SCHEMBL1720238 | 0.73 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118001282-A | Pharmaceutical composition for cancer treatment | 因佩蒂斯生物科学有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | claimed |
| CN-118001282-A | Pharmaceutical composition for cancer treatment | 因佩蒂斯生物科学有限公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-2499142-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | Advinus Therapeutics Limited (IN) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |