Sugi Predict

Sugi Predict / Compounds / SCHEMBL185608

SCHEMBL185608

SCHEMBL185608

N[C@@H](COCc1ccccc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A1 P43005 4/20 0.73
▸ ALPI P09923 1/20 0.58
▸ PKM P14618 1/20 0.58
▸ PTGS1 P23219 1/20 0.58
▸ XIAP P98170 1/20 0.58
▸ SLC7A5 Q01650 1/20 0.58
▸ TACR1 P25103 2/20 0.54
▸ IDO1 P14902 1/20 0.54
▸ SLC1A3 P43003 3/20 0.53
▸ SLC1A2 P43004 3/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ CA1 P00915 3/20 0.51
▸ CA2 P00918 1/20 0.51
▸ CA7 P43166 1/20 0.51
▸ CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561330 1.00 SLC1A1 (0.73) SLC1A1ALPIPKMPTGS1XIAP
SCHEMBL2037281 1.00 SLC1A1 (0.73) SLC1A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL857896 0.98 SLC1A1 (0.71) SLC1A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL29350764 0.98 SLC1A1 (0.71) SLC1A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9989072 0.98 SLC1A1 (0.71) SLC1A1ALPIPKMPTGS1XIAP
SCHEMBL31606701 0.91 SLC1A1 (0.63) SLC1A1ALPIPKMPTGS1XIAP
SCHEMBL20825448 0.91 SLC1A1 (0.63) SLC1A1ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL3580103 0.91 SLC1A1 (0.62) SLC1A1ALPIPKMPTGS1XIAP
SCHEMBL24354993 0.90 SLC1A1 (0.61) SLC1A1ALPIPKMPTGS1XIAP
SCHEMBL18555180 0.89 SLC1A1 (0.60) SLC1A1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS OHIO STATE INNOVATION FOUNDATION (US) 2025-11-20 — — US claimed
US-12404236-B2 Non-peptidic cell-penetrating motifs OHIO STATE INNOVATION FOUNDATION (US) 2025-09-02 — — US claimed
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction OHIO STATE INNOVATION FOUNDATION (US) 2025-06-17 — — US claimed
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION WASHINGTON UNIVERSITY 2025-05-29 — — US claimed
CN-119751538-A Medicine for removing fat or fat pad and application 西安莱格瑞生物科技有限公司 2025-04-04 — — CN claimed
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 — — US claimed
CN-118459380-A Synthesis method of beta-amino alcohol compound containing cyclobutyl 瑞博(苏州)制药有限公司 2024-08-09 — — CN claimed
CN-117815245-A Medicine for removing fat or fat pad and application 西安莱格瑞生物科技有限公司 2024-04-05 — — CN claimed
CN-115724779-B Amide alkyl disulfide compound, preparation method and application thereof 四川大学 2024-03-29 — — CN claimed
US-20240101509-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS OHIO STATE INNOVATION FOUNDATION 2024-03-28 — — US claimed
EP-0521871-A1 ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS THE GILLETTE COMPANY (US) 1993-01-13 — — EP claimed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 — — US claimed
WO-1991011988-A1 ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS THE GILLETTE COMPANY (US) 1991-08-22 — — WO claimed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 — — EP claimed
EP-0051205-B1 TRIDECAPEPTIDE, PROCESS FOR ITS PREPARATION AND ITS USE Dr. Karl Thomae GmbH (DE) 1986-01-02 — — EP claimed
EP-0076557-B1 PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-13 — — EP claimed
US-4483807-A Process for producing a slow release composite JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1984-11-20 — — US claimed
US-4421744-A OPIATE RECEPTOR ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-20 — — US claimed
EP-0076557-A2 Peptides and pseudopeptides in which the N terminus bears two substituents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 — — EP claimed
US-3936469-A Process for preparing N-carboxylic anhydrides of amino acids KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) 1976-02-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404236-B2 Non-peptidic cell-penetrating motifs TIMM50, TIMM10, PITRM1 SLC1A1 798/4885ALPI 4656/4885PKM 1287/4885
US-20240101509-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS TIMM50, TIMM10, PITRM1 SLC1A1 798/4885ALPI 4656/4885PKM 1287/4885
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS TIMM50, TIMM10, PITRM1 SLC1A1 798/4885ALPI 4656/4885PKM 1287/4885
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC SLC1A1 2206/4885ALPI 2312/4885PKM 1286/4885
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION TMPRSS2, PRSS1, PRSS2 SLC1A1 3965/4885ALPI 646/4885PKM 3388/4885
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction CHP1, NFATC1, PPP3R1 SLC1A1 2814/4885ALPI 4341/4885PKM 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.