Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881753 | 0.73 | RAB9A (0.45) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL17144366 | 0.67 | HSD17B10 (0.55) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL29044069 | 0.67 | HPGD (0.50) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL15068474 | 0.67 | HPGD (0.43) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL15068569 | 0.67 | KDM4E (0.43) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL21524868 | 0.67 | HRH4 (0.45) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL5867498 | 0.66 | MAOA (0.56) | RAB9AKDM4EALDH1A1MAOBSMN1; SMN2 | |
| SCHEMBL31004956 | 0.65 | HPGD (0.47) | RAB9AKDM4EALDH1A1MAOBCA12 | |
| SCHEMBL722215 | 0.65 | BACE1 (0.55) | RAB9AKDM4EALDH1A1MAOBTSHR | |
| SCHEMBL16669677 | 0.65 | KDM4E (0.41) | RAB9AKDM4EALDH1A1MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851407-B2 | Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor | CARNEGIE MELLON UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20170058325-A1 | Left-Handed Gamma-Peptide Nucleic Acids, Methods of Synthesis and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-20170058325-A1 | Left-Handed Gamma-Peptide Nucleic Acids, Methods of Synthesis and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851407-B2 | Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor | NPPA, POLL, POLI | RAB9A 4096/4885KDM4E 4837/4885ALDH1A1 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.