SCHEMBL1856484

SCHEMBL1856484

CO[Si](Nc1ccccc1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.42
TSHR P16473 3/20 0.42
IDO1 P14902 3/20 0.42
PTGS2 P35354 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 3/20 0.39
CTSD P07339 1/20 0.39
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL1138187 0.93 TDP1 (0.38) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL980166 0.78 TSHR (0.40) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL1136260 0.75 NPSR1 (0.42) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL9060568 0.74 MEN1 (0.47) TDP1LMNACYP3A4ALDH1A1MEN1
SCHEMBL28548128 0.73 NPSR1 (0.37) TDP1TSHRPTGS2HSD17B10ALDH1A1
SCHEMBL1371114 0.72 TSHR (0.43) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL7691374 0.72 ALDH1A1 (0.53) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL8588125 0.72 HPGD (0.44) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL49520 0.70 TSHR (0.48) TDP1TSHRIDO1PTGS2CYP1A2
SCHEMBL9181403 0.70 TSHR (0.48) TDP1TSHRIDO1PTGS2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113341665-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2025-06-17 CN claimed
CN-117701138-A Aqueous polyurethane dispersion for high-adhesion low-gloss PVC artificial leather surface treatment agent, and preparation method and application thereof 福建汇得新材料有限公司 2024-03-15 CN claimed
US-11613625-B2 Filler for resinous composition, filler-containing slurry composition and filler-containing resinous composition ADMATECHS CO., LTD. (JP) 2023-03-28 US claimed
CN-110191701-B Composition for enhancing protein strength 株式会社LG生活健康 2023-02-21 CN claimed
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US claimed
CN-112638143-B Efficient electromagnetic shielding nano silver paste and preparation method thereof 深圳先进电子材料国际创新研究院 2022-12-27 CN claimed
CN-115466488-A Hollow spherical silicon dioxide epoxy resin composite material and preparation method and application thereof 河南大学 2022-12-13 CN claimed
CN-112681050-B Color-adjustable micro-cover pavement mixture capable of being constructed in humid environment and preparation method thereof 上海应用技术大学 2022-07-12 CN claimed
CN-113341665-A Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2021-09-03 CN claimed
CN-113211903-A Production method of ceramic-filled type hydrocarbon resin copper-clad plate 中国振华集团云科电子有限公司 2021-08-06 CN claimed
CN-106179503-A The catalyst of hexamethylene height selective catalytic oxidation synthesizing cyclohexanol/Ketohexamethylene 南京工程学院 2016-12-07 CN claimed
CN-103252202-B A kind of organosilicon microballoon with single hole hollow structure and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-01-27 CN claimed
CN-104056608-A Boric acid affinity chromatography material for temperature switch, and preparation method and application of boric acid affinity chromatography material BEIJING INST TECHNOLOGY 2014-09-24 CN claimed
CN-103333600-A Preparation method for one-component waterborne polyurethane transparent heat-insulating coating HEFEI INST PHYSICAL SCI CAS 2013-10-02 CN claimed
CN-103252202-A Single-pore hollow-structured organosilicon microspheres and preparation method thereof CHINESE ACAD INST CHEMISTRY 2013-08-21 CN claimed
CN-102863609-A Organic silicon curing agent for epoxy floor paint and preparation method and application thereof CAS GUANGZHOU CHEMISTRY CO LTD 2013-01-09 CN claimed
CN-1831034-A Preparation method of polyimide/silicon dioxide nano hybrid film INST OF PHYSICO CHEMICAL TECH (CN) 2006-09-13 CN claimed
CN-1252136-C Coupling reaction preparation method of polyimide-silicon oxide nano hybrid material UNIV NANJING POLYTECHNICAL (CN) 2006-04-19 CN claimed
CN-1563149-A Coupling reaction preparation method of polyimide-silicon oxide nano hybrid material UNIV NANJING POLYTECHNICAL (CN) 2005-01-12 CN claimed
WO-1998044545-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed