SCHEMBL18565414

SCHEMBL18565414

Cn1c2cc3ccccc3cc2c2c(-c3ccc4c(c3)oc3ccccc34)cccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.39
ALOX5 P09917 1/20 0.37
PRKDC P78527 1/20 0.37
DUSP3 P51452 1/20 0.36
AHR P35869 2/20 0.35
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
HPGD P15428 2/20 0.35
MAP1LC3B Q9GZQ8 1/20 0.34
MAP1LC3A Q9H492 1/20 0.34
NPC1 O15118 5/20 0.34
RAB9A P51151 5/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565385 0.89 ALOX5 (0.41) HCRTR1ALOX5PRKDCAHRKMT2A
SCHEMBL18565453 0.86 TDP1 (0.38) HCRTR1ALOX5PRKDCDUSP3AHR
SCHEMBL18565397 0.84 ALOX5 (0.38) HCRTR1ALOX5PRKDCDUSP3AHR
SCHEMBL18565407 0.82 HCRTR1 (0.43) HCRTR1AHRKMT2AMEN1ALDH1A1
SCHEMBL25681484 0.81 HSD17B10 (0.40) AHRKMT2AMEN1ALDH1A1MAPT
SCHEMBL25681617 0.81 HSD17B10 (0.40) AHRKMT2AMEN1ALDH1A1MAPT
SCHEMBL18565411 0.81 HCRTR1 (0.42) HCRTR1AHRKMT2AMEN1ALDH1A1
SCHEMBL18565482 0.80 ALOX5 (0.38) HCRTR1ALOX5PRKDCAHRKMT2A
SCHEMBL18565417 0.79 ALOX5 (0.37) ALOX5ALDH1A1MAPTHPGDNPC1
SCHEMBL21718314 0.78 PRKDC (0.34) HCRTR1ALOX5PRKDCDUSP3AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 HCRTR1 4165/4885ALOX5 888/4885PRKDC 2109/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 HCRTR1 4165/4885ALOX5 888/4885PRKDC 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.