SCHEMBL18565385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18565414	0.89	HCRTR1 (0.39)	ALOX5PRKDCAHRMAPTMEN1
	SCHEMBL18565453	0.86	TDP1 (0.38)	ALOX5PRKDCAHRMAPTMEN1
	SCHEMBL18565482	0.85	ALOX5 (0.38)	ALOX5PRKDCAHRMAPTMEN1
	SCHEMBL18565371	0.84	ALKBH5 (0.45)	ALOX5PRKDCAHRGPR3MAPT
	SCHEMBL16376470	0.83	GPR3 (0.52)	GPR3MAPTMEN1KMT2AKDM4E
	SCHEMBL22906558	0.83	GPR3 (0.47)	GPR3MAPTMEN1KMT2AKDM4E
	SCHEMBL21718242	0.82	ALOX5 (0.42)	ALOX5PRKDCAHRMAPTMEN1
	SCHEMBL20618845	0.82	GPR3 (0.44)	ALOX5GPR3MAPTMEN1KMT2A
	SCHEMBL25681617	0.82	HSD17B10 (0.40)	AHRGPR3MAPTMEN1KMT2A
	SCHEMBL25525202	0.82	KDM4E (0.42)	ALOX5PRKDCAHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.