Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565482

SCHEMBL18565482

SCHEMBL18565482

Cn1c2cccc(-c3ccc4c(c3)oc3ccccc34)c2c2c3ccccc3c3ccccc3c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.38
▸ PRKDC P78527 2/20 0.38
▸ AHR P35869 2/20 0.36
▸ MAPT P10636 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ ALKBH5 Q6P6C2 1/20 0.35
▸ FTO Q9C0B1 1/20 0.35
▸ HCRTR1 O43613 1/20 0.34
▸ RET P07949 1/20 0.33
▸ HSP90AA1 P07900 2/20 0.33
▸ IDO1 P14902 1/20 0.33
▸ MMP12 P39900 1/20 0.32
▸ MMP13 P45452 1/20 0.32
▸ HSP90AB1 P08238 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565464 0.85 PRKDC (0.41) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18565371 0.85 ALKBH5 (0.45) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18565385 0.85 ALOX5 (0.41) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18565474 0.82 AHR (0.40) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL18565453 0.82 TDP1 (0.38) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18587883 0.82 ALKBH5 (0.41) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL22141300 0.81 ALOX5 (0.49) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18565472 0.81 AHR (0.39) PRKDCAHRMAPTMEN1KMT2A
SCHEMBL18565414 0.80 HCRTR1 (0.39) ALOX5PRKDCAHRMAPTMEN1
SCHEMBL18565484 0.79 ALOX5 (0.39) ALOX5PRKDCMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALOX5 888/4885PRKDC 2109/4885AHR 361/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALOX5 888/4885PRKDC 2109/4885AHR 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.