SCHEMBL18565452

SCHEMBL18565452

Cn1c2cc(-c3ccc4c(c3)[Si](C)(C)c3ccccc3-4)ccc2c2c3ccccc3ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.35
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RAB9A P51151 4/20 0.33
NPC1 O15118 2/20 0.33
MAOB P27338 1/20 0.33
NQO2 P16083 1/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
CASP1 P29466 2/20 0.30
CASP7 P55210 2/20 0.30
HSD17B10 Q99714 2/20 0.30
PKM P14618 1/20 0.30
GALK1 P51570 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
SAE1 Q9UBE0 1/20 0.30
UBA2 Q9UBT2 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565461 0.92 KMT2A (0.33) L3MBTL1RXRARXRBRAB9ANQO2
SCHEMBL18565463 0.86 GAA (0.33) GAACASP1CASP7HSD17B10PKM
SCHEMBL18565454 0.85 RXRA (0.34) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL18565449 0.85 TLR4 (0.31) RAB9A
SCHEMBL18565384 0.84 RXRA (0.47) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL18565421 0.83 RXRA (0.36) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL18565487 0.81 MAOB (0.36) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL18565423 0.81 LMNA (0.35) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL22661400 0.80 RXRA (0.50) L3MBTL1RXRARXRBRAB9ANPC1
SCHEMBL18565389 0.79 GPR3 (0.39) L3MBTL1RXRARXRBNQO2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 L3MBTL1 1263/4885RXRA 4249/4885RXRB 4487/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 L3MBTL1 1263/4885RXRA 4249/4885RXRB 4487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.