Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565455

SCHEMBL18565455

SCHEMBL18565455

Cn1c2cccc(-c3ccc4c(c3)sc3ccccc34)c2c2c3ccccc3ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.37
▸ PRNP P04156 1/20 0.36
▸ RAB9A P51151 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ MCL1 Q07820 1/20 0.34
▸ GPR3 P46089 2/20 0.33
▸ S1PR4 O95977 3/20 0.33
▸ S1PR5 Q9H228 3/20 0.33
▸ NQO1 P15559 1/20 0.33
▸ NQO2 P16083 1/20 0.33
▸ F9 P00740 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ PRKDC P78527 1/20 0.31
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565436 0.87 ALOX5 (0.36) ALOX5PRNPRAB9AMAPTALDH1A1
SCHEMBL18565383 0.86 ALOX5 (0.41) ALOX5RAB9AMAPTALDH1A1HPGD
SCHEMBL18565417 0.86 ALOX5 (0.37) ALOX5RAB9AMAPTALDH1A1HPGD
SCHEMBL18588333 0.85 PRKDC (0.33) PRKDC
SCHEMBL18565447 0.84 RAB9A (0.38) PRNPRAB9AMAPTALDH1A1HPGD
SCHEMBL18565441 0.84 RAB9A (0.38) PRNPRAB9AMAPTALDH1A1HPGD
SCHEMBL18565484 0.83 ALOX5 (0.39) ALOX5RAB9AMAPTALDH1A1HPGD
SCHEMBL18565453 0.79 TDP1 (0.38) ALOX5MAPTALDH1A1HPGDPRKDC
SCHEMBL18566284 0.78 KDM4E (0.42) MAPTALDH1A1HPGDMCL1GPR3
SCHEMBL13506960 0.77 ALOX5 (0.36) ALOX5RAB9AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALOX5 888/4885PRNP 2653/4885RAB9A 1488/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALOX5 888/4885PRNP 2653/4885RAB9A 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.