SCHEMBL18565484

SCHEMBL18565484

Cn1c2cccc(-c3ccc4c(c3)sc3ccccc34)c2c2c3ccccc3c3ccccc3c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
MAPT P10636 7/20 0.37
ALDH1A1 P00352 4/20 0.37
RAB9A P51151 3/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALKBH5 Q6P6C2 1/20 0.36
FTO Q9C0B1 1/20 0.36
GPR3 P46089 2/20 0.35
RET P07949 1/20 0.34
IDO1 P14902 2/20 0.33
HSP90AA1 P07900 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PRKDC P78527 1/20 0.32
F12 P00748 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
MAPK1 P28482 2/20 0.31
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565468 0.86 ALOX5 (0.39) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18565374 0.86 ALKBH5 (0.45) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18565383 0.86 ALOX5 (0.41) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18565471 0.83 RAB9A (0.40) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL18565455 0.83 ALOX5 (0.37) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18587883 0.83 ALKBH5 (0.41) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL12698463 0.82 ALOX5 (0.49) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18565479 0.82 MAPT (0.39) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL18565417 0.81 ALOX5 (0.37) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18565436 0.80 ALOX5 (0.36) ALOX5MAPTALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALOX5 888/4885MAPT 1057/4885ALDH1A1 2977/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALOX5 888/4885MAPT 1057/4885ALDH1A1 2977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.