Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152603 | 1.00 | MDM4 (0.62) | MDM4MDM2NPSR1ALDH1A1LNPEP | |
| SCHEMBL4149820 | 0.95 | MDM4 (0.67) | MDM4MDM2NPSR1ALDH1A1HDAC1 | |
| SCHEMBL4153058 | 0.95 | MDM4 (0.67) | MDM4MDM2NPSR1ALDH1A1HDAC1 | |
| SCHEMBL4153061 | 0.95 | MDM4 (0.67) | MDM4MDM2NPSR1ALDH1A1HDAC1 | |
| SCHEMBL4149824 | 0.95 | MDM4 (0.67) | MDM4MDM2NPSR1ALDH1A1HDAC1 | |
| SCHEMBL29352083 | 0.89 | ALDH1A1 (0.50) | MDM4MDM2NPSR1ALDH1A1LNPEP | |
| SCHEMBL21466071 | 0.89 | ALDH1A1 (0.50) | MDM4MDM2NPSR1ALDH1A1LNPEP | |
| SCHEMBL1859205 | 0.88 | MDM4 (0.56) | MDM4MDM2NPSR1ALDH1A1LNPEP | |
| SCHEMBL9203104 | 0.87 | MDM4 (0.64) | MDM4MDM2NPSR1ALDH1A1LNPEP | |
| SCHEMBL29648509 | 0.87 | NPSR1 (0.63) | MDM4MDM2NPSR1ALDH1A1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | claimed |
| EP-1876169-A1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2008-01-09 | — | — | EP | claimed |
| EP-1923075-B1 | Radiopaque polymeric stents | UNIV RUTGERS (US) | 2015-11-11 | — | — | EP | disclosed |
| CN-101180267-B | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTV | 2015-06-17 | — | — | CN | disclosed |
| US-8546612-B2 | Phenyl-N-acyl derivatives of amines and amino acids, a process for the preparation thereof, a pharmaceutical composition and use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2013-10-01 | — | — | US | disclosed |
| US-8546612-B2 | Phenyl-N-acyl derivatives of amines and amino acids, a process for the preparation thereof, a pharmaceutical composition and use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2013-10-01 | — | — | US | disclosed |
| US-8546612-B2 | Phenyl-N-acyl derivatives of amines and amino acids, a process for the preparation thereof, a pharmaceutical composition and use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2013-10-01 | — | — | US | disclosed |
| US-8436201-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8436201-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8436201-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-20130109880-A1 | PHENYL-N-ACYL DERIVATIVES OF AMINES AND AMINO ACIDS, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION AND USE THEREOF | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2013-05-02 | — | — | US | disclosed |
| US-7935843-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-05-03 | — | — | US | disclosed |
| US-7935843-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-05-03 | — | — | US | disclosed |
| US-7935843-B2 | Functionalized diphenolics and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
| EP-1876169-A1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2008-01-09 | — | — | EP | disclosed |
| US-20070135355-A1 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070135355-A1 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070135355-A1 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135355-A1 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM | DDT, DHCR7, NOTUM | MDM4 1769/4885MDM2 993/4885NPSR1 271/4885 |
| US-20130109880-A1 | PHENYL-N-ACYL DERIVATIVES OF AMINES AND AMINO ACIDS, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION AND USE THEREOF | MAOA, PAH, MAOB | MDM4 4734/4885MDM2 4398/4885NPSR1 443/4885 |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | MDM4 4681/4885MDM2 4424/4885NPSR1 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.