SCHEMBL18566147

SCHEMBL18566147

Cn1c2ccccc2c2ccc3c(oc4ccc5ccccc5c43)c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.44
FTO Q9C0B1 1/20 0.44
GPR3 P46089 1/20 0.42
HSP90AA1 P07900 1/20 0.40
IDO1 P14902 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 4/20 0.37
HSD17B10 Q99714 4/20 0.37
TSHR P16473 3/20 0.37
HIF1A Q16665 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
STAT6 P42226 1/20 0.37
HNF4A P41235 1/20 0.37
HPGD P15428 4/20 0.36
CYP3A4 P08684 3/20 0.36
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22483126 0.81 L3MBTL1 (0.45) KDM4EMAPTL3MBTL1TDP1CYP1A2
SCHEMBL13183690 0.80 ALKBH5 (0.50) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL18566151 0.80 ALKBH5 (0.44) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL23966487 0.80 ALKBH5 (0.53) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL18566118 0.79 L3MBTL1 (0.43) KDM4EMAPTL3MBTL1TDP1CYP1A2
SCHEMBL257568 0.78 ALKBH5 (0.58) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL13789696 0.78 L3MBTL1 (0.52) KDM4EMAPTL3MBTL1TDP1CYP1A2
SCHEMBL11914244 0.77 ALKBH5 (0.50) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL17741723 0.77 KDM4E (0.43) KDM4EMAPTL3MBTL1TDP1CYP1A2
SCHEMBL18416284 0.76 ALKBH5 (0.56) ALKBH5FTOGPR3HSP90AA1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885GPR3 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.