SCHEMBL18566151

SCHEMBL18566151

Cn1c2ccccc2c2ccc3c4cc5ccccc5cc4oc3c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.44
FTO Q9C0B1 1/20 0.44
GPR3 P46089 1/20 0.42
HSP90AA1 P07900 1/20 0.40
IDO1 P14902 1/20 0.40
KDM4E B2RXH2 9/20 0.38
HSD17B10 Q99714 6/20 0.38
ALDH1A1 P00352 6/20 0.38
HPGD P15428 6/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KIF11 P52732 1/20 0.37
GAA P10253 3/20 0.35
PKM P14618 1/20 0.35
CASP1 P29466 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13183690 0.83 ALKBH5 (0.50) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL18566141 0.83 PGR (0.36) ALKBH5FTOKDM4EALDH1A1HPGD
SCHEMBL17876752 0.81 KDM4E (0.45) KDM4EHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL18566147 0.80 ALKBH5 (0.44) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL25993585 0.80 ALKBH5 (0.41) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL25682265 0.80 KIF11 (0.43) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL21031744 0.80 GPR3 (0.39) GPR3KDM4EHSD17B10ALDH1A1HPGD
SCHEMBL25683283 0.79 ALKBH5 (0.40) ALKBH5FTOGPR3HSP90AA1IDO1
SCHEMBL19382732 0.79 KDM4E (0.33) HSP90AA1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL25993584 0.79 ALKBH5 (0.40) ALKBH5FTOGPR3HSP90AA1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885GPR3 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.