Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900537 | 0.94 | PDK2 (0.51) | PDK2PTPRCTDP1RARARARB | |
| SCHEMBL133477 | 0.91 | PDK2 (0.66) | PDK2PTPRCTDP1ATML3MBTL1 | |
| SCHEMBL1552743 | 0.91 | PDK2 (0.66) | PDK2PTPRCTDP1ATML3MBTL1 | |
| SCHEMBL16313987 | 0.91 | PDK2 (0.47) | PDK2PTPRCL3MBTL1ALDH1A1RARA | |
| SCHEMBL12337045 | 0.88 | PDK2 (0.60) | PDK2PTPRCTDP1ATML3MBTL1 | |
| SCHEMBL134286 | 0.86 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL134285 | 0.86 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL29114 | 0.86 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL13702055 | 0.85 | PDK2 (0.57) | PDK2PTPRCTDP1ATML3MBTL1 | |
| SCHEMBL13702054 | 0.83 | PDK2 (0.55) | PDK2TDP1ATML3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888706-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |