Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568873 | 0.85 | KDM4E (0.38) | KDM4ETSHRALDH1A1POLBTDP1 | |
| SCHEMBL1653093 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL1653960 | 0.75 | CNKSR1 (0.43) | TSHRALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL18568888 | 0.74 | POLB (0.36) | KDM4EALDH1A1POLBCRHBPCRHR2 | |
| SCHEMBL1652986 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1POLBCRHBPCRHR2 | |
| SCHEMBL1653438 | 0.71 | NOD2 (0.37) | KDM4ETSHRALDH1A1POLBCRHBP | |
| SCHEMBL18568603 | 0.70 | CDC7 (0.40) | KDM4EALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL18568868 | 0.70 | KDM4E (0.39) | KDM4ETSHRALDH1A1POLBTDP1 | |
| SCHEMBL12783330 | 0.70 | NOD2 (0.36) | KDM4ETSHRALDH1A1POLBTDP1 | |
| SCHEMBL1653451 | 0.70 | RAB9A (0.38) | KDM4ETSHRALDH1A1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |