Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18569117 | 0.86 | TUBB4A (0.30) | — | |
| SCHEMBL18569008 | 0.86 | ACMSD (0.32) | SLC6A9 | |
| SCHEMBL18568730 | 0.84 | — | — | |
| SCHEMBL1655822 | 0.83 | PTGDR2 (0.33) | PTGDR2SLC6A9FFAR1LTA4HDGAT1 | |
| SCHEMBL18568936 | 0.83 | — | — | |
| SCHEMBL18568661 | 0.83 | ABL1 (0.31) | — | |
| SCHEMBL18569102 | 0.83 | PTPRC (0.33) | SLC6A9DGAT1 | |
| SCHEMBL18568658 | 0.82 | — | — | |
| SCHEMBL18569107 | 0.81 | CYP1A1 (0.33) | — | |
| SCHEMBL18568906 | 0.81 | BTK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |