Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.33 |
| ▸ | PTPRG | P23470 | 2/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568661 | 0.92 | ABL1 (0.31) | ABL1BCR | |
| SCHEMBL18568906 | 0.91 | BTK (0.35) | ABL1BCR | |
| SCHEMBL18569107 | 0.90 | CYP1A1 (0.33) | KMT2AABL1BCRXDH | |
| SCHEMBL18569117 | 0.85 | TUBB4A (0.30) | — | |
| SCHEMBL18568959 | 0.84 | — | — | |
| SCHEMBL18569000 | 0.84 | RIPK1 (0.38) | KMT2AABL1BCR | |
| SCHEMBL18569008 | 0.84 | ACMSD (0.32) | ACMSDSLC6A9 | |
| SCHEMBL18568953 | 0.83 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL18568915 | 0.83 | — | — | |
| SCHEMBL18569093 | 0.83 | PTGDR2 (0.33) | SLC6A9DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |