Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13047492 | 0.82 | MAPT (0.44) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL290269 | 0.80 | PAX8 (0.43) | MEN1MAPTKMT2ACYP3A4CYP1A2 | |
| SCHEMBL25581884 | 0.80 | MAPT (0.38) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL18569016 | 0.80 | CYP3A4 (0.56) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL13074523 | 0.78 | NPC1 (0.48) | RAB9ANPC1MEN1KMT2AALOX5 | |
| SCHEMBL18569363 | 0.78 | RAB9A (0.48) | RAB9ANPC1MAPTALOX5CYP3A4 | |
| SCHEMBL14636639 | 0.78 | CYP1A2 (0.52) | MEN1MAPTKMT2AALOX5CYP3A4 | |
| SCHEMBL14637387 | 0.78 | MEN1 (0.47) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL13047484 | 0.78 | CDC7 (0.43) | MEN1MAPTKMT2ACYP3A4CYP1A2 | |
| SCHEMBL25580818 | 0.78 | PIK3CG (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |