Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568866 | 0.90 | GAA (0.68) | GAAL3MBTL1MEN1KMT2AALDH1A1 | |
| Ubisindine SCHEMBL191543 | 0.81 | TSHR (0.62) | GAAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8273732 | 0.80 | ALDH1A1 (0.50) | GAAL3MBTL1ALDH1A1HPGDFFAR1 | |
| SCHEMBL18569319 | 0.80 | GAA (0.44) | GAAL3MBTL1ALDH1A1HPGDFFAR1 | |
| SCHEMBL27091877 | 0.79 | CNR2 (0.49) | GAAMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL19976649 | 0.79 | L3MBTL1 (0.57) | GAAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8273178 | 0.79 | GAA (0.55) | GAAL3MBTL1ALDH1A1FFAR1KDM4E | |
| SCHEMBL22781472 | 0.79 | GAA (0.55) | GAAL3MBTL1ALDH1A1HPGDFFAR1 | |
| SCHEMBL17366180 | 0.79 | GAA (0.55) | GAAL3MBTL1ALDH1A1HPGDFFAR1 | |
| SCHEMBL9893329 | 0.78 | TOP1 (0.52) | GAAL3MBTL1ALDH1A1HPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786773-B1 | ISOINDOLIN-1-ONE DERIVATIVES | CANCER RES TECH LTD (GB) | 2017-03-01 | — | — | EP | disclosed |