Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929366 | 0.96 | SRC (0.45) | HTR7RAD52GAAALDH1A1SRC | |
| SCHEMBL5929424 | 0.94 | HRH3 (0.46) | HTR7RAD52ALDH1A1POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL5929367 | 0.93 | HRH3 (0.45) | HTR7RAD52ALDH1A1POLBMAPK1 | |
| SCHEMBL18570638 | 0.91 | GAA (0.45) | HTR7RAD52GAAALDH1A1HTT | |
| SCHEMBL14419464 | 0.90 | POLB (0.54) | RAD52ALDH1A1POLBMAPK1ATM | |
| SCHEMBL6840686 | 0.89 | HRH3 (0.46) | ALDH1A1HRH3BACE1 | |
| SCHEMBL15986268 | 0.86 | CHRM2 (0.38) | HTR7RAD52GAAALDH1A1POLB | |
| SCHEMBL5929421 | 0.85 | ADRA2A (0.43) | RAD52GAAALDH1A1CYP3A4THRB | |
| SCHEMBL15986208 | 0.84 | ALDH1A1 (0.35) | HTR7RAD52GAAALDH1A1POLB | |
| SCHEMBL6142477 | 0.84 | ACHE (0.45) | RAD52GAAALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734179-B1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO KGAA (DE) | 2017-03-01 | — | — | EP | disclosed |