SCHEMBL1857166

SCHEMBL1857166

Oc1ccc(O)c(-c2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
PTPN5 P54829 2/20 0.49
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
MAPT P10636 1/20 0.46
CNR2 P34972 1/20 0.46
RORC P51449 1/20 0.44
RORB Q92753 1/20 0.44
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
PELI1 Q96FA3 1/20 0.43
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
KDM4E B2RXH2 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30073274 0.84 P2RX1 (0.47) MAPTCNR2ESR1ESR2KDM4E
SCHEMBL1864157 0.84 P2RX1 (0.47) MAPTCNR2ESR1ESR2KDM4E
SCHEMBL9056918 0.83 PTPN5 (0.48) ALOX15ALOX12PTPN5THRATHRB
SCHEMBL30689246 0.82 PTPN5 (0.69) ALOX15ALOX12PTPN5MAPTCNR2
SCHEMBL2048141 0.82 PTPN5 (0.69) ALOX15ALOX12PTPN5MAPTCNR2
SCHEMBL28212393 0.82 THRA (0.41) ALOX15ALOX12PTPN5THRATHRB
SCHEMBL13867738 0.81 PELI1 (0.53) MAPTESR1ESR2PELI1HSD17B1
SCHEMBL28609510 0.80 KIF11 (0.61) THRBESR1ESR2PELI1KDM4E
SCHEMBL322331 0.80 RORB (0.52) THRATHRBMAPTRORCRORB
SCHEMBL28146422 0.80 AKR1C3 (0.43) ALOX15ALOX12PTPN5MAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773603-B Hyperbranched polyarylethersulfone copolymer containing platinum aromatic alkynyl group and preparation method thereof 吉林大学 2023-09-05 CN claimed
CN-113372556-B Polyarylether sulfone copolymer with main chain containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2022-09-23 CN claimed
CN-114773603-A Hyperbranched polyarylethersulfone copolymer containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2022-07-22 CN claimed
CN-113372556-A Polyarylether sulfone copolymer with main chain containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2021-09-10 CN claimed
CN-109603589-B Ag @ NH2-MIL-125/polyarylethersulfone hybridized compact reactive ultrafiltration membrane and preparation method thereof 东北师范大学 2021-02-05 CN claimed
CN-108250384-B Simple method for preparing fluorine-containing polyurethane monodisperse microspheres with high yield 济南大学 2020-09-01 CN claimed
CN-114773603-B Hyperbranched polyarylethersulfone copolymer containing platinum aromatic alkynyl group and preparation method thereof 吉林大学 2023-09-05 CN disclosed
CN-113372556-B Polyarylether sulfone copolymer with main chain containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2022-09-23 CN disclosed
CN-114773603-A Hyperbranched polyarylethersulfone copolymer containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2022-07-22 CN disclosed
CN-113372556-A Polyarylether sulfone copolymer with main chain containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2021-09-10 CN disclosed
CN-108641083-B High-temperature-resistant ultraviolet fluorescent polyether sulfone copolymer, preparation method and copolymer film 吉林大学 2021-08-10 CN disclosed
US-20210207031-A1 LIQUID CRYSTAL ALIGNMENT FILM, METHOD FOR PRODUCING THE SAME, SUBSTRATE AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-07-08 US disclosed
CN-109603589-B Ag @ NH2-MIL-125/polyarylethersulfone hybridized compact reactive ultrafiltration membrane and preparation method thereof 东北师范大学 2021-02-05 CN disclosed
US-7947800-B2 Poly(aryl ether) with pendent sulfonic acid phenyl groups NATIONAL RESEARCH COUNCIL OF CANADA 2011-05-24 US disclosed
US-20090203806-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-08-13 US disclosed
EP-2046862-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS National Research Council of Canada (CA) 2009-04-15 EP disclosed
WO-2008009102-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-01-24 WO disclosed
CN-1651482-A Method of synthesizing fluorine containing superbranched light wave conductive material based on A2+B3 type monomer reaction UNIV JILIN (CN) 2005-08-10 CN disclosed
CN-1190452-C High-performance material of soluble controlled crosslinkable polyarylether ketone and preparation thereof UNIV JILIN (CN) 2005-02-23 CN disclosed
CN-1482158-A High-performance material of soluble controlled crosslinkable polyarylether ketone and preparation thereof 吉林大学 2004-03-17 CN disclosed