SCHEMBL18573537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18573642	0.93	NPC1 (0.63)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL12900100	0.85	HDAC6 (0.55)	NPC1RAB9AESRRGHDAC6SMN1; SMN2
	SCHEMBL6246675	0.82	HDAC6 (0.72)	NPC1RAB9AHDAC6SMN1; SMN2KMT2A
	SCHEMBL18573457	0.80	PTPN1 (0.63)	NPC1RAB9APTPN1PTPN11HDAC6
	SCHEMBL18573575	0.79	HDAC6 (0.62)	NPC1RAB9AHDAC6SMN1; SMN2KMT2A
	SCHEMBL14849810	0.78	NPC1 (1.00)	NPC1RAB9APPARGNCOA2NCOA1
	SCHEMBL12900103	0.78	FABP3 (0.53)	NPC1RAB9AESRRGHDAC6SMN1; SMN2
	SCHEMBL14566332	0.77	HDAC6 (0.51)	NPC1RAB9AESRRGHDAC6SMN1; SMN2
	SCHEMBL18573523	0.77	HPGD (0.54)	NPC1RAB9AESRRGHDAC6SMN1; SMN2
	SCHEMBL18573588	0.76	HDAC6 (0.58)	NPC1RAB9AHDAC6SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.