Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573579 | 0.81 | KMT2A (0.48) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18573585 | 0.79 | HPGD (0.43) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18573580 | 0.79 | HSD17B1 (0.55) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL20310142 | 0.75 | RAB9A (0.43) | ACKR3HPGDSRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23222410 | 0.74 | ALDH1A1 (0.57) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18573588 | 0.72 | HDAC6 (0.58) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18573590 | 0.72 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6264976 | 0.69 | ALDH1A1 (0.49) | HPGDSRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL23110055 | 0.66 | ACKR3 (0.62) | ACKR3RAB9ANPC1HPGDKDM4E | |
| SCHEMBL18573543 | 0.65 | KDM4E (0.52) | HPGDSRAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017034242-A2 | NOVEL CATECHOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 유영제약 | 2017-03-02 | — | — | WO | disclosed |