Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837825 | 0.91 | HTR7 (0.83) | HTR7LMNAHTR1BCYP1A2CYP2C19 | |
| SCHEMBL20621345 | 0.81 | HTR7 (0.69) | HTR7LMNAHTR1BDRD2DRD1 | |
| SCHEMBL10798879 | 0.81 | HTR7 (0.67) | HTR7LMNACYP1A2CYP2C19KDM4E | |
| SCHEMBL25388128 | 0.80 | HTR7 (0.66) | HTR7LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3888894 | 0.80 | LMNA (0.86) | HTR7LMNAHTR1BDRD2DRD1 | |
| SCHEMBL701534 | 0.79 | HTR7 (0.64) | HTR7LMNACYP1A2CYP2C19KDM4E | |
| SCHEMBL2344935 | 0.79 | HTR7 (0.64) | HTR7LMNACYP1A2CYP2C19KDM4E | |
| SCHEMBL14647148 | 0.79 | HTR7 (0.65) | HTR7HTR1BDRD2DRD1DRD4 | |
| SCHEMBL8352887 | 0.78 | HTR7 (0.65) | HTR7HTR1BDRD2DRD1DRD4 | |
| SCHEMBL2459518 | 0.78 | HTR7 (0.65) | HTR7HTR1BDRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
| US-20110105608-A1 | MODULATORS OF NUCLEAR RECEPTOR CO-REGULATORY PROTEIN BINDING | NORTHEASTERN UNIVERSITY (US) | 2011-05-05 | — | — | US | disclosed |
| WO-2009117739-A1 | MODULATORS OF NUCLEAR RECEPTOR CO-REGULATORY PROTEIN BINDING | NORTHEASTERN UNIVERSITY (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-1999002509-A1 | PROCESS FOR PREPARING TRI-ARYL-ALKYLALKENES | SMITHKLINE BEECHAM PLC (GB) | 1999-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105608-A1 | MODULATORS OF NUCLEAR RECEPTOR CO-REGULATORY PROTEIN BINDING | ESRRB, ESRRA, ESRRG | HTR7 2704/4885LMNA 4071/4885HTR1B 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.