Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 3/20 | 0.31 |
| ▸ | ACE | P12821 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573595 | 0.83 | LMNA (0.55) | HSD17B10LMNACYP2C19RENACE | |
| SCHEMBL12704221 | 0.80 | HSD17B10 (0.38) | HSD17B10LMNACYP2C19DPP4PREP | |
| SCHEMBL26167163 | 0.80 | LMNA (0.33) | HSD17B10LMNACYP2C19DPP4POLB | |
| SCHEMBL20416167 | 0.76 | KMT2A (0.40) | POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL22296753 | 0.75 | POLB (0.33) | HSD17B10LMNACYP2C19POLBL3MBTL1 | |
| SCHEMBL24287714 | 0.72 | HSD17B10 (0.40) | HSD17B10LMNACYP2C19POLB | |
| SCHEMBL26433850 | 0.72 | POLB (0.31) | POLBL3MBTL1 | |
| SCHEMBL18592162 | 0.72 | POLB (0.35) | DPP4POLBDPP8L3MBTL1 | |
| SCHEMBL23073833 | 0.71 | DPP4 (0.35) | DPP4PREPPOLBDPP8DPP9 | |
| SCHEMBL18536645 | 0.71 | ITGB1 (0.51) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035401-A1 | AMIDE COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |