Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748405 | 0.83 | HSD17B10 (0.58) | HSD17B10NPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL26054412 | 0.82 | HSD17B10 (0.47) | HSD17B10NPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL22296753 | 0.75 | POLB (0.33) | HSD17B10LMNACYP2C19POLB | |
| SCHEMBL12520006 | 0.74 | HPGD (0.41) | SMN1; SMN2TSHRALDH1A1POLBMEN1 | |
| SCHEMBL18576765 | 0.72 | HSD17B10 (0.36) | HSD17B10LMNACYP2C19POLB | |
| SCHEMBL18583793 | 0.72 | POLB (0.39) | HSD17B10SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL11386799 | 0.71 | FKBP1A (0.44) | HSD17B10NPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL15820254 | 0.71 | ACE (0.40) | HSD17B10LMNACYP2C19POLB | |
| SCHEMBL14816941 | 0.70 | HSD17B10 (0.62) | HSD17B10NPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14845549 | 0.70 | HSD17B10 (0.62) | HSD17B10NPC1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985002-A1 | ARYL, HETEROARY, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |