Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369766 | 1.00 | MAPK1 (0.50) | MAPK1MEN1KMT2ANPC1LMNA | |
| SCHEMBL1857686 | 0.84 | LMNA (0.50) | MEN1KMT2ANPC1LMNATSHR | |
| SCHEMBL8953727 | 0.84 | LMNA (0.50) | MEN1KMT2ANPC1LMNATSHR | |
| SCHEMBL1862886 | 0.84 | LMNA (0.54) | MAPK1MEN1KMT2ANPC1LMNA | |
| SCHEMBL1857683 | 0.84 | LMNA (0.50) | MEN1KMT2ANPC1LMNATSHR | |
| SCHEMBL4365310 | 0.84 | LMNA (0.50) | MEN1KMT2ANPC1LMNATSHR | |
| SCHEMBL19361684 | 0.83 | KMT2A (0.50) | MAPK1MEN1KMT2ANPC1LMNA | |
| SCHEMBL14524001 | 0.83 | LOXL2 (0.52) | MAPK1MEN1KMT2ANPC1LMNA | |
| SCHEMBL16131783 | 0.83 | LOXL2 (0.52) | MAPK1MEN1KMT2ANPC1LMNA | |
| SCHEMBL25518745 | 0.83 | KMT2A (0.52) | MAPK1MEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311631-A1 | Biosynthetic Production of 4-Amino 4-Deoxychorismate (Adc) and [3R,4R]-4-Amino-3-Hydroxycyclohexa-1,5-Diene-1-Carboxylic Acid (3,4-Cha) | DSM IP ASSETS B. V. (NL) | 2008-12-18 | — | — | US | disclosed |
| EP-1888760-A1 | BIOSYNTHETIC PRODUCTION OF (5S,6S)-6-AMINO-5-HYDROXYCYCLOHEXA-1,3-DIENE-1-CARBOXYLIC ACID (2,3-CHA) | DSM IP ASSETS B.V. (NL) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006128706-A1 | BIOSYNTHETIC PRODUCTION OF (5S,6S)-6-AMINO-5-HYDROXYCYCLOHEXA-1,3-DIENE-1-CARBOXYLIC ACID (2,3-CHA) | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |
| EP-1728872-A1 | Biosynthetic production of (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid (2,3-CHA) | DSM IP Assets B.V. (NL) | 2006-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311631-A1 | Biosynthetic Production of 4-Amino 4-Deoxychorismate (Adc) and [3R,4R]-4-Amino-3-Hydroxycyclohexa-1,5-Diene-1-Carboxylic Acid (3,4-Cha) | HPD, DHPS, PGD | MAPK1 3910/4885MEN1 4879/4885KMT2A 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.