Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024146 | 0.93 | AKT1 (0.48) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1854421 | 0.92 | MEN1 (0.50) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1024008 | 0.88 | KMT2A (0.48) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1020939 | 0.84 | MEN1 (0.51) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1259156 | 0.83 | MEN1 (0.50) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1072867 | 0.82 | SYK (0.47) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL4853602 | 0.82 | SYK (0.47) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1024580 | 0.81 | MMP1 (0.44) | MEN1KMT2AGAAIDO1AKT1 | |
| SCHEMBL1022823 | 0.81 | AKT1 (0.48) | MEN1KMT2AIDO1AKT1CTSL | |
| SCHEMBL4856502 | 0.80 | SYK (0.48) | MEN1KMT2AGAAIDO1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697400-B1 | BIPHENYL-SUBSTITUTED ANTIBACTERIAL MACROCYCLES | AICURIS GMBH & CO KG (DE) | 2011-05-25 | — | — | EP | disclosed |
| US-20050256037-A1 | Antibacterial amide macrocyles | BAYER HEALTHCARE AG (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256037-A1 | Antibacterial amide macrocyles | AADAC, PAM, NOD2 | MEN1 1754/4885KMT2A 2507/4885GAA 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.