Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18577906 | 0.85 | CA12 (0.32) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577905 | 0.83 | CYP3A4 (0.34) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577916 | 0.82 | CYP1A2 (0.33) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577886 | 0.82 | CYP1A2 (0.33) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577922 | 0.82 | CYP1A2 (0.33) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577891 | 0.82 | CYP1A2 (0.33) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18633388 | 0.81 | CA12 (0.39) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18577908 | 0.81 | CA12 (0.36) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL14822353 | 0.78 | CA12 (0.39) | CA12CA2CA9CA1CYP3A4 | |
| SCHEMBL18589191 | 0.78 | CA12 (0.32) | CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141537-B1 | A LABELING PRECURSOR COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDIPHYSICS CO LTD (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10081620-B2 | Radioactive fluorine labeling precursor compound and method for manufacturing radioactive fluorine labeled compound using the same | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2018-09-25 | — | — | US | disclosed |
| EP-3141537-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081620-B2 | Radioactive fluorine labeling precursor compound and method for manufacturing radioactive fluorine labeled compound using the same | AFF1, NPFFR1, AFF2 | HDAC1 2217/4885HDAC6 2148/4885TRPM8 4829/4885 |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | AFF1, NPFFR1, AFF2 | HDAC1 2217/4885HDAC6 2148/4885TRPM8 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.