Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18577886 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL18577891 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL18577916 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL18577905 | 0.97 | CYP3A4 (0.34) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL18577899 | 0.86 | CA2 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL18633388 | 0.84 | CA12 (0.39) | CYP3A4CYP2C19CA12CA1CA2 | |
| SCHEMBL26657800 | 0.83 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL18577895 | 0.82 | HDAC1 (0.35) | CYP3A4CA12CA1CA2CA9 | |
| SCHEMBL18589129 | 0.81 | CA12 (0.38) | CYP3A4CYP2C19CA12CA1CA2 | |
| SCHEMBL14822353 | 0.81 | CA12 (0.39) | CYP3A4CYP2C19CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081620-B2 | Radioactive fluorine labeling precursor compound and method for manufacturing radioactive fluorine labeled compound using the same | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2018-09-25 | — | — | US | disclosed |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081620-B2 | Radioactive fluorine labeling precursor compound and method for manufacturing radioactive fluorine labeled compound using the same | AFF1, NPFFR1, AFF2 | CYP1A2 142/4885CYP3A4 551/4885CYP2C9 663/4885 |
| US-20170066748-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | AFF1, NPFFR1, AFF2 | CYP1A2 142/4885CYP3A4 551/4885CYP2C9 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.