SCHEMBL185790

SCHEMBL185790

C#CC(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.41
TAAR1 Q96RJ0 4/20 0.41
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAOB P27338 1/20 0.38
ALDH1A1 P00352 1/20 0.38
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyne SCHEMBL22499804 0.97 MIF (0.40) MIFTAAR1ADRA2AADRA2CCYP2D6
Alcohol SCHEMBL28345560 0.89 LMNA (0.43) TAAR1ADRA2AADRA2CLMNAHIF1A
SCHEMBL29636144 0.83 MIF (0.33) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL9303811 0.78 MIF (0.44) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL2867417 0.78 MIF (0.44) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL17530144 0.77 CHRNA7 (0.41) ALDH1A1
SCHEMBL8733281 0.76 MIF (0.43) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL5797292 0.75 ADRB2 (0.50) ADRA2ALMNAHIF1AKDM4EALDH1A1
SCHEMBL17134315 0.75
SCHEMBL15203081 0.75 MIF (0.39) MIFTAAR1ADRA2AADRA2CCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117210191-A Packaging adhesive for full-spectrum LED light source and preparation method thereof 中山市木林森电子有限公司 2023-12-12 CN claimed
CN-116178965-A Heat conduction silicone grease and assembly thereof 北京中石伟业科技无锡有限公司 2023-05-30 CN claimed
CN-107746580-B LIM low-oil-powder separation high-conductivity silicone rubber composition and preparation method thereof 平湖阿莱德实业有限公司 2023-05-05 CN claimed
CN-116004011-A High-temperature-resistant double-component organic silicon composition and preparation method thereof 上海普力通新材料科技有限公司 2023-04-25 CN claimed
CN-114181643-A High-temperature-resistant and high-viscosity silica gel label and preparation method thereof 江苏皇冠新材料科技有限公司 2022-03-15 CN claimed
CN-108329347-B Method for preparing β -chloroalkenylphosphono derivatives 苏州大学 2020-05-01 CN claimed
CN-106083669-A A kind of method being prepared β chlorine alkene sulfone compound by sulfinate and alkynes 湖南大学 2016-11-09 CN claimed
EP-0885883-B1 FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF MITSUBISHI PHARMA CORP (JP) 2006-11-02 EP claimed
EP-0669935-B1 COMPOUNDS USEFUL AS SWEETENING AGENTS AND PROCESS FOR THEIR PREPARATION NOFRE CLAUDE (FR) 1996-06-05 EP claimed
EP-0543919-B1 USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES SEARLE & CO (US) 1996-04-10 EP claimed
EP-0669935-A1 COMPOUNDS USEFUL AS SWEETENING AGENTS AND PROCESS FOR THEIR PREPARATION. NOFRE CLAUDE (FR) 1995-09-06 EP claimed
WO-1994011391-A1 COMPOUNDS USEFUL AS SWEETENING AGENTS AND PROCESS FOR THEIR PREPARATION NOFRE CLAUDE (FR) 1994-05-26 WO claimed
EP-0161877-B1 1,4-DIHYDROPYRIDINE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1991-05-29 EP claimed
JP-62039606-A None JP disclosed
EP-4745196-A1 RESIN COMPOSITION LG Chem, Ltd. (KR) 2026-05-20 EP disclosed
EP-4745194-A1 ENDOTHERMIC PAD LG Chem, Ltd. (KR) 2026-05-20 EP disclosed
EP-0091291-B1 ROOM TEMPERATURE STABLE, HEAT ACTIVATED ORGANOPOLYSILOXANE COMPOSITIONS Toray Silicone Company Limited (JP) 1987-05-13 EP disclosed
JP-S6239606-A PRODUCTION OF POLYPHENYLETHYNYLACETYLENE AND PHENYL DERIVATIVE THEREOF AGENCY OF IND SCIENCE & TECHNOL 1987-02-20 JP disclosed
US-4465818-A Room temperature stable, heat activated organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1984-08-14 US disclosed
EP-0091291-A2 Room temperature stable, heat activated organopolysiloxane compositions Toray Silicone Company Limited (JP) 1983-10-12 EP disclosed