Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073432 | 0.88 | TSHR (0.39) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL1489418 | 0.83 | ALOX15 (0.42) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL757712 | 0.83 | — | — | |
| SCHEMBL17727677 | 0.81 | TSHR (0.37) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28746790 | 0.80 | FAAH (0.41) | TSHRSMN1; SMN2MAPTALDH1A1FAAH | |
| Urea SCHEMBL27483216 | 0.77 | ALDH1A1 (0.44) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL1961289 | 0.77 | TSHR (0.43) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL30508394 | 0.77 | CA12 (0.43) | TSHRMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL4855330 | 0.77 | TDP1 (0.35) | TSHRKMT2A | |
| SCHEMBL253528 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10718960-B2 | Method for producing contact lenses with wearing comfort | ALCON INC. (CH) | 2020-07-21 | — | — | US | disclosed |
| EP-3532276-A1 | METHOD FOR PRODUCING SURFACE COATED CONTACT LENSES WITH WEARING COMFORT | Novartis AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-3344447-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON | Novartis AG (CH) | 2018-07-11 | — | — | EP | disclosed |
| US-20180120590-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH WEARING COMFORT | ALCON INC. (CH) | 2018-05-03 | — | — | US | disclosed |
| US-9810812-B2 | Method for producing contact lenses with durable lubricious coatings thereon | NOVARTIS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20170068019-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON | ALCON INC. (CH) | 2017-03-09 | — | — | US | disclosed |