SCHEMBL1858148

SCHEMBL1858148

CCCCCCCCCCCCCCCC(=O)Oc1ccccc1C(=O)O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.88
MEN1 O00255 2/20 0.88
KMT2A Q03164 2/20 0.88
RECQL P46063 1/20 0.88
HSD17B10 Q99714 6/20 0.55
HPGD P15428 4/20 0.55
POLM Q9NP87 2/20 0.54
POLK Q9UBT6 2/20 0.54
POLL Q9UGP5 2/20 0.54
POLH Q9Y253 2/20 0.54
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.54
ESR1 P03372 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
HMGB1 P09429 1/20 0.54
GGT1 P19440 1/20 0.54
PTGS1 P23219 1/20 0.54
PTGS2 P35354 1/20 0.54
BLM P54132 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390528 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL29135334 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL28956887 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL725982 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL6328818 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL727072 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL16800398 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL44212 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL7706618 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10
SCHEMBL10697059 1.00 KDM4E (0.88) KDM4EMEN1KMT2ARECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150374839-A1 NOVEL FATTY ACID-SALICYLATE CONJUGATES WITH ENHANCED THERAPEUTIC PROPERTIES KEAN UNIVERSITY (US) 2015-12-31 US disclosed
US-20150374839-A1 NOVEL FATTY ACID-SALICYLATE CONJUGATES WITH ENHANCED THERAPEUTIC PROPERTIES KEAN UNIVERSITY (US) 2015-12-31 US disclosed
US-9056139-B2 Fatty acid-salicylate conjugates with enhanced therapeutic properties KEAN UNIVERSITY (US) 2015-06-16 US disclosed
US-9056139-B2 Fatty acid-salicylate conjugates with enhanced therapeutic properties KEAN UNIVERSITY (US) 2015-06-16 US disclosed
US-7977040-B2 Sharp images; medical diagnosis; mixture of photosensitive silver halide emulsion, organic silver salt, reducing agents and binder on support FUJIFILM CORPORATION (JP) 2011-07-12 US disclosed
EP-2323844-A1 GELATINOUS ELASTOMER COMPOSITIONS Silipos Inc. (US) 2011-05-25 EP disclosed
WO-2010148104-A2 TOPICAL COMPOSITIONS CONTAINING A POLYMER FOR RELEASING AT LEAST ONE SALICYLIC ACID COMPOUND L'OREAL S.A. (FR) 2010-12-23 WO disclosed
CN-101744739-A Use of an ester derived from 4-carboxy-2-pyrrolidinone as a solvent in cosmetic compositions and cosmetic compositions containing the ester OREAL 2010-06-23 CN disclosed
WO-2010030824-A1 GELATINOUS ELASTOMER COMPOSITIONS SILIPOS, INC. (US) 2010-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374839-A1 NOVEL FATTY ACID-SALICYLATE CONJUGATES WITH ENHANCED THERAPEUTIC PROPERTIES FASN, ELOVL1, ELOVL3 KDM4E 2152/4885MEN1 4457/4885KMT2A 2301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.