Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.88 |
| ▸ | RECQL | P46063 | 1/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.54 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.54 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.54 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390528 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL29135334 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL28956887 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL725982 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL727072 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL16800398 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL44212 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL7706618 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL1858148 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL10697059 | 1.00 | KDM4E (0.88) | KDM4EMEN1KMT2ARECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55062018-A | — | — | None | — | — | JP | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| WO-2011098839-A2 | DI-ASPIRIN DERIVATIVES | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2011-08-18 | — | — | WO | disclosed |
| US-20100255598-A1 | Medication Adherence Monitoring System | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2010-10-07 | — | — | US | disclosed |
| US-6909012-B2 | Diflunisal esters and related compounds | UNIVERSITY OF QUEENSLAND (AU) | 2005-06-21 | — | — | US | disclosed |
| US-20030220497-A1 | Novel diflunisal esters and related compounds | THE UNIVERSITY OF QUEENSLAND | 2003-11-27 | — | — | US | disclosed |
| US-6593365-B1 | Method for treating and/or controlling thrombosis in a mammal, comprising administering to a mammal in need thereof an effective dosage of a compound having the formula: | THE UNIVERSITY OF QUEENSLAND (AU) | 2003-07-15 | — | — | US | disclosed |
| WO-1998046234-A1 | NOVEL DIFLUNISAL ESTERS AND RELATED COMPOUNDS | THE UNIVERSITY OF QUEENSLAND (AU) | 1998-10-22 | — | — | WO | disclosed |
| JP-S5562018-A | ANTIPYRETIC, ANALGESIC, AND ANTIPHLOGISTIC | MARUKO SEIYAKU KK | 1980-05-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220497-A1 | Novel diflunisal esters and related compounds | HPGDS, ALOX12, ALOX15 | KDM4E 3349/4885MEN1 4715/4885KMT2A 4790/4885 |
| US-20130035317-A1 | Di-Aspirin Derivatives | SDHA, DLD, DPYD | KDM4E 2764/4885MEN1 3500/4885KMT2A 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.