SCHEMBL1858467

SCHEMBL1858467

N#[N+]c1ccc(F)c([N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HIF1A Q16665 1/20 0.56
VCAM1 P19320 1/20 0.53
CA1 P00915 1/20 0.45
MMP2 P08253 1/20 0.45
CA14 Q9ULX7 1/20 0.45
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 6/20 0.42
HTT P42858 4/20 0.42
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
MITF O75030 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RECQL P46063 1/20 0.37
ESPL1 Q14674 1/20 0.37
CASP6 P55212 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11877292 0.95 ALDH1A1 (0.51) ALDH1A1HIF1AVCAM1CA1MMP2
SCHEMBL11881555 0.95 ALDH1A1 (0.51) ALDH1A1HIF1AVCAM1CA1MMP2
Trifluoromethanesulfonic Acid SCHEMBL11503459 0.88 VCAM1 (0.50) ALDH1A1HIF1AVCAM1CA1MMP2
SCHEMBL1858469 0.81 ALDH1A1 (0.35) ALDH1A1HIF1AVCAM1CA1MMP2
SCHEMBL12625747 0.81 ALDH1A1 (0.56) ALDH1A1HIF1AVCAM1CA1MMP2
SCHEMBL6651702 0.78 TSHR (0.55) ALDH1A1TDP1LMNAMAPTMEN1
SCHEMBL14733275 0.78 MAPT (0.59) ALDH1A1HIF1ACA1LMNAMAPT
Hydrochloric Acid SCHEMBL11577241 0.76 VCAM1 (0.53) VCAM1TDP1TSHRMAPK1
SCHEMBL695248 0.76 MAPT (0.53) ALDH1A1HIF1ACA1LMNAMAPT
SCHEMBL28937850 0.76 VCAM1 (0.49) VCAM1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846383-B2 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-12-07 US claimed
US-20080145945-A1 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US claimed
US-7935538-B2 Indicator immobilization on assay devices KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-05-03 US disclosed
US-7846383-B2 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-12-07 US disclosed
EP-2091485-A2 LATERAL FLOW ASSAY DEVICE AND ABSORBENT ARTICLE CONTAINING SAME Kimberly-Clark Worldwide, Inc. (US) 2009-08-26 EP disclosed
EP-2092332-A1 INDICATOR IMMOBILIZATION ON ASSAY DEVICES Kimberly-Clark Worldwide, Inc. (US) 2009-08-26 EP disclosed
WO-2008075217-A2 LATERAL FLOW ASSAY DEVICE AND ABSORBENT ARTICLE CONTAINING SAME KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-06-26 WO disclosed
WO-2008075216-A1 INDICATOR IMMOBILIZATION ON ASSAY DEVICES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-06-26 WO disclosed
US-20080145949-A1 Indicator immobilization on assay devices KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US disclosed
US-20080145945-A1 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US disclosed
EP-0140256-B1 COMPOSITION FOR EXAMINING UROBILINOGEN WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-01-25 EP disclosed
US-4665038-A RED COLOR WITH 9-FLUORENONE-2-DIAZONIUM SALT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-12 US disclosed
EP-0140256-A2 Composition for examining urobilinogen WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-05-08 EP disclosed
US-3989462-A DIAZONIUM SALTS RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3989462-A DIAZONIUM SALTS RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed