Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324430 | 0.87 | CYP11B1 (0.39) | L3MBTL1PTGDR2ALDH1A1HTTKMT2A | |
| SCHEMBL18586988 | 0.85 | L3MBTL1 (0.43) | F2PLAUST14L3MBTL1PTGDR2 | |
| SCHEMBL18586252 | 0.83 | KDM4E (0.48) | F2PLAUST14L3MBTL1ALDH1A1 | |
| SCHEMBL8161648 | 0.80 | ALDH1A1 (0.44) | L3MBTL1PTGDR2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL23648160 | 0.79 | SLC6A4 (0.45) | L3MBTL1PTGDR2ALDH1A1HTTKMT2A | |
| SCHEMBL11835026 | 0.78 | L3MBTL1 (0.46) | L3MBTL1PTGDR2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1440131 | 0.78 | CYP1A2 (0.54) | L3MBTL1ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL11443005 | 0.78 | MAPK1 (0.52) | F2PLAUST14L3MBTL1ALDH1A1 | |
| SCHEMBL2103750 | 0.76 | PKM (0.65) | PTGDR2 | |
| SCHEMBL285799 | 0.76 | MCHR1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239869-B2 | Sulfonamide compounds as voltage-gated sodium channel modulators | LUPIN LIMITED (IN) | 2019-03-26 | — | — | US | disclosed |
| EP-3344621-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS | Lupin Limited (IN) | 2018-07-11 | — | — | EP | disclosed |
| US-20180186777-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2018-07-05 | — | — | US | disclosed |
| WO-2017037682-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239869-B2 | Sulfonamide compounds as voltage-gated sodium channel modulators | SCN7A, SCN1A, SCN5A | F2 4428/4885PLAU 4716/4885ST14 1296/4885 |
| US-20180186777-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS | SCN7A, SCN1A, SCN5A | F2 4428/4885PLAU 4716/4885ST14 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.