SCHEMBL1858631

SCHEMBL1858631

CCO[Si](C)(C)CN1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
MAPK1 P28482 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
GAA P10253 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 4/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
HTR2A P28223 1/20 0.36
SCN1A P35498 1/20 0.36
HTR2B P41595 1/20 0.36
KCNH2 Q12809 1/20 0.36
SCN2A Q99250 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
SCN3A Q9NY46 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
USP2 O75604 2/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776777 0.83 TSHR (0.38) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL31468509 0.83 KDM4E (0.33) KDM4E
SCHEMBL787845 0.83 TSHR (0.38) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL4002631 0.79 SIGMAR1 (0.33) SMN1; SMN2SIGMAR1CXCR4POLB
SCHEMBL4058410 0.79
SCHEMBL31687752 0.79 TSHR (0.36) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL2797041 0.79 SMN1; SMN2 (0.46) TSHRMAPK1SMN1; SMN2GAAALDH1A1
SCHEMBL1859823 0.77 SMN1; SMN2 (0.40) TSHRMAPK1SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL4070474 0.76
SCHEMBL19768733 0.75 MAPK1 (0.33) TSHRMAPK1SMN1; SMN2GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025547-A Side chain amino silicone oil and preparation method thereof 山东东岳有机硅材料股份有限公司 2025-05-23 CN disclosed
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed
US-8197591-B2 Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof ECKART GMBH (DE) 2012-06-12 US disclosed
EP-1904587-B8 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING (ALPHA)-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2011-05-25 EP disclosed
EP-1904587-B1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2010-11-03 EP disclosed
US-20090249979-A1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2009-10-08 US disclosed
EP-1904587-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCITON THEREOF Eckart GmbH (DE) 2008-04-02 EP disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
WO-2007098887-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING α-SILANES AND METHOD FOR THE PRODUCITON THEREOF ECKART GMBH (DE) 2007-09-07 WO disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 TSHR 2049/4885MAPK1 2701/4885SMN1; SMN2 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.