Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687752 | 0.92 | TSHR (0.36) | TSHRMAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL2382706 | 0.88 | MAPK1 (0.33) | TSHRMAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL19768733 | 0.87 | MAPK1 (0.33) | TSHRMAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL2385305 | 0.86 | — | — | |
| SCHEMBL2384105 | 0.86 | — | — | |
| SCHEMBL25211866 | 0.83 | ALDH1A1 (0.41) | TSHRMAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1858631 | 0.83 | TSHR (0.38) | TSHRMAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL776777 | 0.83 | TSHR (0.38) | TSHRMAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL2383064 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL2381809 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208509-B1 | CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2024-02-28 | — | — | EP | claimed |
| EP-4157943-B1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2024-01-31 | — | — | EP | claimed |
| CN-114307260-B | Preparation method of polyether composition | 南京瑞思化学技术有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115155113-B | Structure for organic silicon defoamer and synthesis method thereof | 佛山市南海大田化学有限公司 | 2023-09-29 | — | — | CN | claimed |
| US-20230235174-A1 | CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2023-07-27 | — | — | US | claimed |
| CN-115105868-B | Organic silicon defoamer and preparation method thereof | 佛山市南海大田化学有限公司 | 2023-07-18 | — | — | CN | claimed |
| US-20230183427-A1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2023-06-15 | — | — | US | claimed |
| WO-2023099015-A1 | PROCESS FOR PREPARING ORGANOSILICON COMPOUNDS CONTAINING ORGANYLOXY GROUPS | WACKER CHEMIE AG (DE) | 2023-06-08 | — | — | WO | claimed |
| CN-114316610-B | Preparation method of organic silicon emulsion | 南京瑞思化学技术有限公司 | 2023-05-23 | — | — | CN | claimed |
| EP-4157943-A1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2023-04-05 | — | — | EP | claimed |
| CN-114316299-A | Method for improving stability of organic silicon emulsion | 南京瑞思化学技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114316610-A | Preparation method of organic silicon emulsion | 南京瑞思化学技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114307260-A | Preparation method of polyether composition | 南京瑞思化学技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| EP-3215227-B1 | OXIDATIVE HAIR DYE COMPOSITION COMPRISING A COMBINATION OF CROSS LINKED AMINATED SILOXANPOLYMERS AND NON IONIC TENSIDS | HENKEL AG & CO KGAA (DE) | 2019-03-13 | — | — | EP | claimed |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | claimed |
| EP-3215227-A1 | OXIDATION DYE, CONTAINING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | Henkel AG & Co. KGaA (DE) | 2017-09-13 | — | — | EP | claimed |
| US-9758689-B2 | Silver nanoparticle inks comprising aminomethylsilanes | XEROX CORPORATION (US) | 2017-09-12 | — | — | US | claimed |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2017-08-17 | — | — | US | claimed |
| US-9637600-B2 | Cross-linkable masses based on organosilicon compounds | WACKER CHEMIE AG (DE) | 2017-05-02 | — | — | US | claimed |
| WO-2016071024-A1 | OXIDATION DYE, CONTAINING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2016-05-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | KRT18, PLOD3, SORD | TSHR 4320/4885MAPK1 1744/4885SMN1; SMN2 4023/4885 |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | KRT18, PLOD3, SORD | TSHR 4320/4885MAPK1 1744/4885SMN1; SMN2 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.