SCHEMBL776777

SCHEMBL776777

CCO[Si](C)(CN1CCOCC1)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
MAPK1 P28482 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
GAA P10253 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 5/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
HTR2A P28223 1/20 0.36
SCN1A P35498 1/20 0.36
HTR2B P41595 1/20 0.36
KCNH2 Q12809 1/20 0.36
SCN2A Q99250 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
SCN3A Q9NY46 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
USP2 O75604 2/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19768731 0.87 MAPK1 (0.33) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL2502894 0.84
SCHEMBL787845 0.83 TSHR (0.38) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL1992740 0.83 HRH3 (0.31) HRH3
SCHEMBL2501931 0.83 HRH3 (0.31) HRH3
SCHEMBL1858631 0.83 TSHR (0.38) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL4058923 0.81
SCHEMBL538138 0.79 SIGMAR1 (0.36) SMN1; SMN2SIGMAR1CXCR4POLB
SCHEMBL31687752 0.79 TSHR (0.36) TSHRMAPK1SMN1; SMN2GAAKMT2A
SCHEMBL612357 0.79 SMN1; SMN2 (0.46) TSHRMAPK1SMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113897171-B Preparation method of high-displacement dealcoholized flame-retardant fireproof sealant 成都硅宝科技股份有限公司 2023-02-03 CN claimed
CN-113897171-A Preparation method of high-displacement dealcoholized flame-retardant fireproof sealant 成都硅宝科技股份有限公司 2022-01-07 CN claimed
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US claimed
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US claimed
EP-2010608-A1 TWO-PART TRANSLUCENT SILICONE RUBBER-FORMING COMPOSITION Momentive Performance Materials Inc. (US) 2009-01-07 EP claimed
WO-2007117552-A1 TWO-PART TRANSLUCENT SILICONE RUBBER-FORMING COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-10-18 WO claimed
US-12545809-B2 Moisture-curing conformal coating compositions WACKER CHEMIE AG (DE) 2026-02-10 US disclosed
EP-4172246-B1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2024-08-07 EP disclosed
EP-3024551-B1 PROCESS FOR TREATING THE HAIR WITH AT LEAST ONE SILICONE FUNCTIONALIZED WITH AT LEAST ONE ALKOXYSILANE UNIT, A PARTICULAR SOLVENT AND LESS THAN 2% WATER OREAL (FR) 2024-03-13 EP disclosed
US-20230279263-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2023-09-07 US disclosed
EP-4172246-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS Wacker Chemie AG (DE) 2023-05-03 EP disclosed
CN-115702188-A Moisture-curable conformal coating composition 瓦克化学股份公司 2023-02-14 CN disclosed
CN-113897171-B Preparation method of high-displacement dealcoholized flame-retardant fireproof sealant 成都硅宝科技股份有限公司 2023-02-03 CN disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
WO-2006119916-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2006-11-16 WO disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545809-B2 Moisture-curing conformal coating compositions COL1A1, COL2A1, MSR1 TSHR 2199/4885MAPK1 4078/4885SMN1; SMN2 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.