Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586647 | 0.86 | KDM4E (0.37) | SRCAURKANTRK1KDM4EALDH1A1 | |
| SCHEMBL18586458 | 0.81 | SRC (0.36) | SRCAURKANTRK1TAS1R3TAS1R1 | |
| SCHEMBL18586645 | 0.75 | TRPA1 (0.35) | SRC | |
| SCHEMBL22587303 | 0.74 | ALOX15 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7282855 | 0.74 | MEN1 (0.38) | TAS1R3TAS1R1TAS1R2HPGDSMN1; SMN2 | |
| SCHEMBL25625702 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1LPAR1 | |
| SCHEMBL14543279 | 0.72 | ICMT (0.40) | SRCCDK8CDK19ALDH1A1PRKCE | |
| SCHEMBL18570745 | 0.68 | KDM4E (0.40) | SRCKDM4EALDH1A1PRKCEHPGD | |
| SCHEMBL8256542 | 0.67 | KDM4E (0.41) | SRCKDM4EALDH1A1PRKCEHPGD | |
| SCHEMBL12016053 | 0.67 | IDO1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344599-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow Agrosciences LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017040191-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-03-09 | — | — | WO | disclosed |