SCHEMBL1858709

SCHEMBL1858709

C=CCN(CC=C)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28180512 0.97 PYCR1 (0.31) PYCR1
SCHEMBL2339803 0.81 TSHR (0.33)
SCHEMBL7177724 0.78 ALDH1A1 (0.35)
SCHEMBL11070461 0.78 ALDH1A1 (0.35)
Hydrochloric Acid SCHEMBL7717766 0.74 ALDH1A1 (0.33)
SCHEMBL26348337 0.73 TSHR (0.35)
Bromide SCHEMBL29011443 0.72 ALDH1A1 (0.32)
SCHEMBL4177390 0.72
SCHEMBL41777 0.72
SCHEMBL43114 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395765-A1 INTRAVENOUS FORMULATIONS OF RK-33 Natsar Pharmaceuticals, Inc. (US) 2024-07-10 EP disclosed
WO-2024081018-A1 POTENTIAL THERAPEUTICS FOR FIBROSIS BY BLOCKING THE INCREASE OF A KEY ENZYME THE TEXAS A&M UNIVERSITY SYSTEM (US) 2024-04-18 WO disclosed
WO-2023034743-A1 INTRAVENOUS FORMULATIONS OF RK-33 NATSAR PHARMACEUTICALS, INC. (US) 2023-03-09 WO disclosed
EP-3823454-A1 COMPOUNDS WITH ANTIMICROBIAL PROPERTIES NORTHEASTERN UNIVERSITY (US) 2021-05-26 EP disclosed
WO-2020018173-A1 COMPOUNDS WITH ANTIMICROBIAL PROPERTIES NORTHEASTERN UNIVERSITY (US) 2020-01-23 WO disclosed
WO-2014149084-A2 DDX3 AS A BIOMARKER FOR CANCER AND METHODS RELATED THERETO THE JOHNS HOPKINS UNIVERSITY (US) 2014-09-25 WO disclosed
WO-2014032019-A2 COMPOUNDS AND METHODS OF USE THEREOF FOR TREATING TUMORS GEORGETOWN UNIVERSITY (US) 2014-02-27 WO disclosed
WO-2012064396-A9 NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING GEORGETOWN UNIVERSITY (US) 2012-07-05 WO disclosed
WO-2012064396-A2 NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING GEORGETOWN UNIVERSITY (US) 2012-05-18 WO disclosed
EP-2350086-A2 FUSED DIIMIDAZODIAZEPINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE THEREOF University of Maryland, Baltimore County (US) 2011-08-03 EP disclosed
US-5865951-A USING A NEUTRAL SIZING AGENT AND CATIONIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
CN-1190100-A Aqueous dispersions based on water-soluble polymers ATOCHEM ELF SA (FR) 1998-08-12 CN disclosed
US-5606068-A Acid anhydrides, their preparation and their use RHONE-POULENC RORER S.A. (FR) 1997-02-25 US disclosed
US-5527919-A Process for the preparation of 1-[(1,1'-biphenyl]-4-YL]-methyl-1H-imidazole-5-carboxylic acids ROUSSEL UCLAF (FR) 1996-06-18 US disclosed
US-5493046-A A 1-((4-PHENYL)PHENYL)-METHYLENE)IMIDAZOLE ROUSSEL-UCLAF (FR) 1996-02-20 US disclosed
CN-1100415-A New preparation process for sulphurated derivatives of imidazole and the new intermediates obtained ROUSSEL UCLAF (FR) 1995-03-22 CN disclosed
US-5391732-A Cardiotonic agents, hypotensive agents, antispasmodic agents ROUSSEL-UCLAF (FR) 1995-02-21 US disclosed
EP-0317795-A1 Process for coating metal strip by the coil-coating process for the manufacture of parts being under high thermal stress BASF Lacke + Farben AG (DE) 1989-05-31 EP disclosed
EP-0202419-A2 Lactam-block copolymers AlliedSignal Inc. (US) 1986-11-26 EP disclosed
EP-0012381-B1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING HYDANTOIN GROUPS BAYER AG (DE) 1982-12-15 EP disclosed