Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
| ▸ | MMP9 | P14780 | 6/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043061 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL9570487 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL28043062 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL28040270 | 0.84 | MMP2 (0.43) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL27898507 | 0.84 | MMP2 (0.43) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL28823565 | 0.84 | MMP2 (0.43) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL8936409 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL29033737 | 0.79 | MMP9 (0.57) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL8381021 | 0.77 | SLC1A3 (0.53) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL10420675 | 0.76 | MMP9 (0.55) | MMP2MMP9MMP3MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344257-A1 | NR2B SELECTIVE NMDA-RECEPTOR ANTAGONISTS FOR TREATMENT OF IMMUNE-MEDIATED INFLAMMATORY DISEASES | Westfälische Wilhelms-Universität Münster (DE) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017036880-A1 | NR2B SELECTIVE NMDA-RECEPTOR ANTAGONISTS FOR TREATMENT OF IMMUNE-MEDIATED INFLAMMATORY DISEASES | Westfälische Wilhelms-Universität Münster (DE) | 2017-03-09 | — | — | WO | disclosed |