Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.51 |
| ▸ | MMP9 | P14780 | 8/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043062 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL9570487 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL28043061 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL8936471 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP13ALDH1A1MMP1 | |
| SCHEMBL18587741 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL29033737 | 0.79 | MMP9 (0.57) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL28709482 | 0.77 | MMP9 (0.56) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL2780461 | 0.77 | GAA (0.45) | MMP2MMP9MMP13ALDH1A1MMP1 | |
| SCHEMBL7825144 | 0.76 | MMP9 (0.55) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL10419177 | 0.76 | MMP9 (0.55) | MMP2MMP9MMP3MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |