Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185668 | 0.90 | CCR4 (0.53) | CCR4 | |
| SCHEMBL185247 | 0.88 | CCR4 (0.59) | CCR4 | |
| SCHEMBL185711 | 0.86 | CCR4 (0.70) | CCR4 | |
| SCHEMBL186312 | 0.84 | CCR4 (0.56) | CCR4 | |
| SCHEMBL186432 | 0.82 | CCR4 (0.56) | CCR4 | |
| SCHEMBL356836 | 0.78 | CCR4 (0.69) | CCR4 | |
| SCHEMBL186021 | 0.75 | GRIN1 (0.44) | ALDH1A1 | |
| SCHEMBL185923 | 0.74 | RORC (0.46) | CCR4 | |
| SCHEMBL186085 | 0.74 | CCR4 (0.75) | CCR4 | |
| SCHEMBL357460 | 0.74 | CCR4 (0.79) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401270-A1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | Glaxo Group Limited (GB) | 2012-01-04 | — | — | EP | disclosed |