Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972799 | 0.85 | LMNA (0.47) | HCAR2HSD17B10KMT2AELANELMNA | |
| SCHEMBL27950383 | 0.81 | HCAR2 (0.42) | HCAR2HSD17B10LOXL2KMT2AALOX15 | |
| SCHEMBL6628850 | 0.81 | HCAR2 (0.42) | HCAR2HSD17B10LOXL2KMT2AALOX15 | |
| SCHEMBL27455859 | 0.79 | KMT2A (0.50) | HCAR2HSD17B10KMT2AALOX15LMNA | |
| SCHEMBL380364 | 0.75 | HSD17B10 (0.56) | HSD17B10KMT2ACYP19A1LMNAMEN1 | |
| SCHEMBL27950400 | 0.72 | HCAR2 (0.33) | HCAR2HSD17B10LOXL2 | |
| SCHEMBL31123876 | 0.72 | KMT2A (0.56) | HCAR2HSD17B10KMT2AALOX15LMNA | |
| SCHEMBL876393 | 0.72 | KMT2A (0.56) | HCAR2HSD17B10KMT2AALOX15LMNA | |
| SCHEMBL27672030 | 0.72 | — | — | |
| SCHEMBL465132 | 0.70 | LMNA (0.52) | HSD17B10KMT2AELANELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0673783-B1 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORP (US) | 2000-07-05 | — | — | EP | claimed |
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-2999338-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
| EP-1551830-B1 | HETEROCYCLICALLY SUBSTITUTED INDOLINONES AND THEIR USE AS RECEPTOR TYROSINE KINASE INHIBATORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1551830-A2 | HETEROCYCLICALLY SUBSTITUTED INDOLINONES AND THEIR USE AS RECEPTOR TYROSINE KINASE INHIBATORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004026829-A2 | HETEROCYCLICALLY SUBSTITUTED INDOLINONES AND THEIR USE AS RECEPTOR TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-01 | — | — | WO | disclosed |
| EP-0334289-B1 | HETEROCYCLIC SUBSTITUTED 5,7-DIHYDROPYRROLO (3,2-F) BENZOXAZOL-6-ONES, PROCESS FOR THEIR PREPARATION AND DRUGS CONTAINING SAME | Roche Diagnostics GmbH (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0334289-A1 | Heterocyclic substituted 5,7-dihydropyrrolo (3,2-f) benzoxazol-6-ones, process for their preparation and drugs containing same | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |