Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185926 | 0.81 | HCAR2 (0.48) | HCAR2HSD17B10ALOX15KMT2ALOXL2 | |
| SCHEMBL27972799 | 0.79 | LMNA (0.47) | HCAR2HSD17B10KMT2AMAPTKDM4E | |
| SCHEMBL27950383 | 0.79 | HCAR2 (0.42) | HCAR2HSD17B10ALOX15KMT2ALOXL2 | |
| SCHEMBL13134217 | 0.76 | THRB (0.42) | HCAR2HSD17B10ALOX15KMT2AMAPT | |
| SCHEMBL5170271 | 0.76 | HSD17B10 (0.54) | HSD17B10KMT2AMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10772752 | 0.74 | HSD17B10 (0.52) | HSD17B10ALOX15KMT2AMAPTKDM4E | |
| SCHEMBL1532656 | 0.73 | KMT2A (0.58) | HCAR2HSD17B10ALOX15KMT2AMAPT | |
| SCHEMBL27455859 | 0.73 | KMT2A (0.50) | HCAR2HSD17B10ALOX15KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10604528 | 0.72 | KMT2A (0.61) | HSD17B10ALOX15KMT2AMAPTKDM4E | |
| SCHEMBL6924446 | 0.71 | RAB9A (0.46) | HSD17B10KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456210-A1 | PYRAZOLYL-SUBSTITUTED TRIAZOLOQUINOXALINES | JSW-Research Forschungslabor Gmbh (AT) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053973-A1 | PYRAZOLYL-SUBSTITUTED TRIAZOLOQUINOXALINES | JSW-RESEARCH FORSCHUNGSLABOR GMBH (AT) | 2003-07-03 | — | — | WO | disclosed |
| EP-0088997-A1 | Process for producing burning-out effects on textile materials | CASSELLA Aktiengesellschaft (DE) | 1983-09-21 | — | — | EP | disclosed |