Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 1.00 |
| ▸ | AGXT | P21549 | 3/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716084 | 0.80 | IDO1 (0.67) | IDO1AGXT | |
| SCHEMBL39753 | 0.79 | IDO1 (0.66) | IDO1PYCR1GPR84 | |
| SCHEMBL10656615 | 0.79 | IDO1 (0.65) | IDO1PYCR1SLC6A4CYP3A4GPR84 | |
| SCHEMBL1716147 | 0.79 | IDO1 (0.65) | IDO1AGXT | |
| Hydrochloric Acid SCHEMBL1715172 | 0.79 | IDO1 (0.68) | IDO1AGXT | |
| Hydrochloric Acid SCHEMBL1716080 | 0.77 | IDO1 (0.66) | IDO1AGXT | |
| SCHEMBL932921 | 0.77 | IDO1 (0.62) | IDO1PYCR1SLC6A4GPR84 | |
| SCHEMBL11229326 | 0.77 | IDO1 (0.62) | IDO1PYCR1SLC6A4GPR84MAOB | |
| SCHEMBL30080027 | 0.77 | IDO1 (1.00) | IDO1AGXTCYP3A4 | |
| SCHEMBL992105 | 0.77 | IDO1 (1.00) | IDO1AGXTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272736-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | NOVARTIS AG (CH) | 2018-01-24 | — | — | EP | disclosed |
| EP-3138835-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | NOVARTIS AG (CH) | 2017-03-08 | — | — | EP | disclosed |
| EP-2514743-B1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | NOVARTIS AG (CH) | 2016-12-14 | — | — | EP | disclosed |
| CN-102875413-A | Immunosuppressant compounds and compositions | IRM LLC | 2013-01-16 | — | — | CN | disclosed |
| EP-2514743-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2012-10-24 | — | — | EP | disclosed |
| CN-1791395-B | Immunosuppressant compounds and compositions | IRM LLC | 2012-09-26 | — | — | CN | disclosed |
| US-7939519-B2 | Immunosuppresant compounds and compositions | NOVARTIS AG (CH) | 2011-05-10 | — | — | US | disclosed |
| US-20090036423-A1 | IMMUNOSUPPRESANT COMPOUNDS AND COMPOSITIONS | NOVARTIS PHARMACEUTICALS CORPORATION | 2009-02-05 | — | — | US | disclosed |
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | disclosed |
| CN-1791395-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-21 | — | — | CN | disclosed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | disclosed |
| US-20050014728-A1 | Immunosuppressant compounds and compositions | IRM LLC | 2005-01-20 | — | — | US | disclosed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014728-A1 | Immunosuppressant compounds and compositions | ICOS, EDNRA, NFATC1 | IDO1 28/4885AGXT 3758/4885PYCR1 480/4885 |
| US-20090036423-A1 | IMMUNOSUPPRESANT COMPOUNDS AND COMPOSITIONS | EDNRA, NFATC1, FCGR1A | IDO1 29/4885AGXT 3924/4885PYCR1 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.